Posted on January 30, 2014 by floridadoc
Practice guidelines are a fact of life in modern medicine. They provide clinicians with the best data and the latest consensus on what the data mean for the care of patients.
But they are — or have been — rather slow to react to changes.
Enter HCVguidelines.org, a website that aims to keep up with one of the fastest-moving fields in medicine today — the treatment of hepatitis C virus (HCV) with what are called direct-acting agents.
The website was developed and will be run jointly by the American Association for the Study of Liver Diseases, the Infectious Diseases Society of America, and the International Antiviral Society-USA.
Read more at MedPage Today
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Filed under: EBM, Informatics | Tagged: ebm, gastroenterology, guideline, hepatitis C | Leave a comment »
Posted on December 11, 2013 by floridadoc
In a randomized trial, outcomes were neither better nor worse with early antihypertensive therapy.
A 2013 guideline from the American Stroke Association recommends that we avoid antihypertensive drug therapy during the first 24 hours after onset of acute ischemic stroke unless systolic or diastolic blood pressure (BP) exceeds 220 mm Hg or 120 mm Hg, respectively. (The threshold is 185/110 mm Hg for patients receiving thrombolytic therapy; Stroke 2013; 44:870) The concern is that early BP lowering might worsen stroke outcomes. However, no large randomized trials have tested this theory, until now.
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[PMID]24240777[/PMID]
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Filed under: EBM | Tagged: ebm, hypertension, JAMA, stroke | Leave a comment »
Posted on November 19, 2013 by floridadoc
The American Heart Association (AHA) and American College of Cardiology (ACC) issued 4 new cardiovascular disease prevention guidelines last week on cholesterol treatment, cardiovascular risk assessment, lifestyle management and management of overweight and obesity.
The cholesterol guideline made substantial changes to recommendations about statin use, moving away from specific cholesterol targets and likely increasing the number of patients taking the drugs, according to a press release.
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Filed under: Cardiology, EBM | Tagged: cardiology, CVD, ebm, statin | Leave a comment »
Posted on October 12, 2013 by floridadoc
The below data details it fairly well…

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Filed under: EBM, Informatics | Tagged: ebm, health informatics, probability, statistics | Leave a comment »
Posted on October 12, 2013 by floridadoc
Although these findings are observational and require confirmation in a randomized trial, they suggest that achieving ideal systolic blood pressure at the expense of low diastolic BP is not advantageous in adults with chronic kidney disease. While awaiting updated BP recommendations in forthcoming guideline revisions, clinicians should pay close attention to the diastolic pressure when treating systolic hypertension in these patients.
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Filed under: CKD, EBM, Nephrology, Primary Care Topics | Tagged: blood pressure, ckd, ebm | Leave a comment »